Cytogenetic Abnormalities

Author: S. Zneimer
Publisher: John Wiley & Sons
ISBN: 1118412567
Size: 74.89 MB
Format: PDF, Mobi
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Cytogenetic Abnormalities. This guide discusses chromosomal abnormalities and how best to report and communicate lab findings in research and clinical settings. Providing a standard approach to writing cytogenetic laboratory reports, the guide further covers useful guidance on implementing International System for Human Cytogenetic Nomenclature in reports. Part one of the guide explores chromosomal, FISH, and microarray analysis in constitutional cytogenetic analyses, while part two looks at acquired abnormalities in cancers. Both sections provide illustrative examples of chromosomal abnormalities and how to communicate these findings in standardized laboratory reports.

Human Cytogenetics Malignancy And Acquired Abnormalities

Author: Denise E. Rooney
Publisher: Oxford University Press, USA
ISBN: 9780199638413
Size: 23.87 MB
Format: PDF, ePub, Mobi
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Human Cytogenetics Malignancy And Acquired Abnormalities. The advent of molecular technologies has lead to a rapid acceleration in the cytogenetic study of malignancy and acquired abnormalities. As well as having a chapter devoted to molecular technologies (FISH, PRINS, and CGH), molecular methodology is emphasized in all chapters, for example the role of CGH in solid tumour cytogenetics. Classical techniques are not forgotten, with a detailed description of the preparation and analysis of chromosomes from bone marrow and leukaemic blood. This is followed by three chapters on the specific methodology for the cytogenetic study of myeloid leukaemia, acute lymphoblastic leukaemia, and lymphomas and lymphoproliferative disorders. Also covered are chromosome instability syndromes, mutagen-induced chromosome damage in lymphocytes and the role of cytogenetics in the assessment of haematological disorders. This book will be invaluable to any scientists using cytogenetics to study malignancy and along with its sister volume Human Cytogenetics: Constitutional Analysis will be an essential purchase for any cytogenetics laboratory. The volumes are available individually or as a set.

Hematology And Coagulation

Author: Amer Wahed
Publisher: Elsevier
ISBN: 0128003812
Size: 13.79 MB
Format: PDF, ePub, Mobi
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Hematology And Coagulation. Hematology and Coagulation is a clear and easy-to-read presentation of core topics and detailed case studies that illustrate the application of hematopathology knowledge to everyday patient care. In order to be successful, as well as to pass the American Board of Pathology examination, all pathology residents must have a good command of hematopathology, including the challenging topics of hematology and coagulation. Hematology and Coagulation meets this challenge head on. This basic primer offers practical examples of how things function in the hematopathology clinic as well as useful lists, sample questions, and a bullet-point format ideal for quick pre-board review. This book provides only the most clinically relevant examples designed to educate senior medical students, residents and fellows and "refresh" the knowledge base, without overwhelming students, residents, and clinicians. Takes a practical and easy-to-read approach to understanding hematology and coagulation at an appropriate level for both board preparation as well as a professional refresher course Covers all important clinical information found in larger textbooks in a more succinct and easy-to-understand manner Covers essential concepts in hematopathology in such a way that fellows and clinicians understand the methods without having to become specialists in the field

The Principles Of Clinical Cytogenetics

Author: Steven Gersen
Publisher: Springer Science & Business Media
ISBN: 1592598331
Size: 64.50 MB
Format: PDF, Mobi
View: 2004

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The Principles Of Clinical Cytogenetics. This thoroughly revised and expanded edition of a highly praised classic, The Principles of Clinical Cytogenetics, includes the many advances that have occurred in the field. Among the highlights are a full section devoted to advances in fluorescence in situ hybridization (FISH) technology, increased coverage of cancer cytogenetics-both hematopoietic neoplasms and tumor cytogenetics-and new chapters on chromosome instability and the cytogenetics of infertility. The book offers physicians who depend on the cytogenetics laboratory for the diagnosis of their patients, students in cytogenetics programs, and cytogeneticists the clear understanding they need to carry out and interpret their test results rapidly.

Chronic Myeloproliferative Disorders

Author: Barbara J. Bain
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805573073
Size: 53.28 MB
Format: PDF
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Chronic Myeloproliferative Disorders. This publication provides a comprehensive and up-to-date review of the significance of cytogenetic and molecular genetic abnormalities in the chronic myeloid leukaemias and other myeloproliferative disorders. This book will therefore be an important reference text, not only for haematologists, but also for molecular geneticists and cytogeneticists, and anyone involved in leukaemia research.

Mechanisms Of Oncogenesis

Author: Domenico Coppola
Publisher: Springer Science & Business Media
ISBN: 9789048137251
Size: 76.40 MB
Format: PDF, ePub
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Mechanisms Of Oncogenesis. This book offers a comprehensive update on mechanisms of tumorigenesis. The first portion discusses pediatric cancer, the influence of environmental factors and oncogene activity in tumorigenesis; the second portion is structured by organ site for easy access.

Neoplastic Hematopathology

Author: Cherie H. Dunphy, MD
Publisher: Demos Medical Publishing
ISBN: 1617051101
Size: 23.91 MB
Format: PDF, ePub, Mobi
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Neoplastic Hematopathology. Neoplastic Hematopathology provides a concise, visual approach to guide practicing pathologists, hematopathologists, hematologists, oncologists, internists, and trainees to a clear analysis and diagnosis of myeloid and lymphoid specimens. Coverage is comprehensive and for each entity includes a short text description of the key points of the entity- definition; morphologic features; special stains, immunohistochemistry and flow cytometry techniques; differential diagnosis; diagnostic features; special issues (e.g., prognostic or other considerations to note). Images in Neoplastic Hematopathology highlight differential diagnostic features, especially the correlation and integration of standard H & E stains with molecular and immunologic techniques. Neoplastic Hematopathology: An Atlas and Concise Guide features: Clear, concise coverage across the wide range of hematopathologic entities based on the current World Health Organization (WHO) classification Topics selected on the basis of "must-know" entities for the practicing pathologist or trainee Emphasis on integration of routine and special stains with immunologic and molecular techniques, reflecting the most current standards of practice Outstanding images selected to highlight key differential points and potentially misleading variants

Hematopoietic Neoplasms Controversies In Diagnosis And Classification An Issue Of Surgical Pathology Clinics

Author: Tracey I George
Publisher: Elsevier Health Sciences
ISBN: 032327787X
Size: 61.80 MB
Format: PDF, ePub, Mobi
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Hematopoietic Neoplasms Controversies In Diagnosis And Classification An Issue Of Surgical Pathology Clinics . Topics in Hematopoietic Neoplasms: Controversies in Diagnosis and Classification include: ABC vs GC subtyping of diffuse large B cell lymphoma-Does it matter?; Clonal link between malignant lymphoma and histiocytic tumors; Diagnostic criteria for grey zone lymphoma: Are there any?; Diagnostic criteria for primary cutaneous B cell lymphoma; Distinguishing reactive and leukemic large granular lymphocyte proliferations; Differential diagnosis of erythroleukemia; Early pre-T ALL versus MPAL: Diagnostic criteria; Myeloid neoplasms with inv(3) or t(3;3); Update on classification and prognosis in myelodysplastic syndrome; Approach to atypical immunophenotypes in Hodgkin lymphoma; Blastic plasmacytoid dendritic cell tumor: How do you distinguish it from acute myeloid leukemia?; The differential diagnosis of eosinophilia in neoplastic hematopathology; Transformation in myeloproliferative neoplasms; and Challenges in consolidated reporting of hematopoietic neoplasms. This publication is an extremely useful and practical source for pathologists working with this spectrum of disorders. As with all publications in this series, Differential Diagnosis is the main focus of discussion. Staging, Diagnosis, Prognosis, and summaries of Pitfalls in working with these pathologies are presented along with ample figures.